Read fitted binding curves — read_mst_fit

Reads the curves MO.Affinity Analysis fitted to each merge set, from the Fit-Values sheet of Compare Results (Chart) and Dose-Response (Grouped) exports.

Usage

read_mst_fit_curve(path)

Arguments

path: Path to an .xlsx file exported from MO.Affinity Analysis, or a .moc or .nta project file.

Value

A tibble with one row per point on each curve, with columns series, merge_set, target, ligand_concentration, fnorm, response_type and response. response is the curve in the units the data was exported in (see response_type); fnorm is the same curve as Fnorm. Some exports leave the curves empty, giving a tibble with no rows.

Examples

read_mst_fit_curve(tidymst_example("dsnppr10_compare-delta-fnorm.xlsx"))
#> # A tibble: 300 × 7
#>    series merge_set     target ligand_concentration fnorm response_type response
#>     <int> <chr>         <chr>                 <dbl> <dbl> <chr>            <dbl>
#>  1      1 dsnPPR10 RNA… RNAat…           0.00000223  841. delta_fnorm      -220.
#>  2      1 dsnPPR10 RNA… RNAat…           0.00000207  841. delta_fnorm      -220.
#>  3      1 dsnPPR10 RNA… RNAat…           0.00000192  841. delta_fnorm      -219.
#>  4      1 dsnPPR10 RNA… RNAat…           0.00000179  841. delta_fnorm      -219.
#>  5      1 dsnPPR10 RNA… RNAat…           0.00000166  841. delta_fnorm      -219.
#>  6      1 dsnPPR10 RNA… RNAat…           0.00000154  841. delta_fnorm      -219.
#>  7      1 dsnPPR10 RNA… RNAat…           0.00000143  841. delta_fnorm      -219.
#>  8      1 dsnPPR10 RNA… RNAat…           0.00000133  842. delta_fnorm      -219.
#>  9      1 dsnPPR10 RNA… RNAat…           0.00000123  842. delta_fnorm      -219.
#> 10      1 dsnPPR10 RNA… RNAat…           0.00000115  842. delta_fnorm      -219.
#> # ℹ 290 more rows